
Advanced Therapies and Eczema.
Advanced Therapies and Eczema.
Advanced Therapies and Eczema.
Uncover new eczema treatments and their mechanisms, examples, and side effects.
Uncover new eczema treatments and their mechanisms, examples, and side effects.
Uncover new eczema treatments and their mechanisms, examples, and side effects.
2021-10-14T00:00:00.000Z
2021-10-14T00:00:00.000Z
2021-10-14T00:00:00.000Z
Introduction - New Eczema Treatments
If you're looking for innovative solutions to manage your eczema, new eczema treatments are revolutionizing the way we tackle this skin condition. In this blog post, we will explore the mechanisms behind topical calcineurin inhibitors, biologics, and phototherapy. We will also provide specific examples and discuss potential side effects to help you better understand these cutting-edge treatments.
Topical Calcineurin Inhibitors: Taming the Immune System
Topical calcineurin inhibitors, like Tacrolimus and Pimecrolimus, work by dampening the immune system's response, reducing inflammation and itchiness. These non-steroidal creams inhibit calcineurin, a protein that activates immune cells called T-cells, which contribute to eczema symptoms.
Examples:
Tacrolimus (Protopic)
Pimecrolimus (Elidel)
Potential Side Effects:
Burning or stinging sensation at the application site
Redness or irritation
Increased risk of infections due to suppressed immune response
Introduction - New Eczema Treatments
If you're looking for innovative solutions to manage your eczema, new eczema treatments are revolutionizing the way we tackle this skin condition. In this blog post, we will explore the mechanisms behind topical calcineurin inhibitors, biologics, and phototherapy. We will also provide specific examples and discuss potential side effects to help you better understand these cutting-edge treatments.
Topical Calcineurin Inhibitors: Taming the Immune System
Topical calcineurin inhibitors, like Tacrolimus and Pimecrolimus, work by dampening the immune system's response, reducing inflammation and itchiness. These non-steroidal creams inhibit calcineurin, a protein that activates immune cells called T-cells, which contribute to eczema symptoms.
Examples:
Tacrolimus (Protopic)
Pimecrolimus (Elidel)
Potential Side Effects:
Burning or stinging sensation at the application site
Redness or irritation
Increased risk of infections due to suppressed immune response
Introduction - New Eczema Treatments
If you're looking for innovative solutions to manage your eczema, new eczema treatments are revolutionizing the way we tackle this skin condition. In this blog post, we will explore the mechanisms behind topical calcineurin inhibitors, biologics, and phototherapy. We will also provide specific examples and discuss potential side effects to help you better understand these cutting-edge treatments.
Topical Calcineurin Inhibitors: Taming the Immune System
Topical calcineurin inhibitors, like Tacrolimus and Pimecrolimus, work by dampening the immune system's response, reducing inflammation and itchiness. These non-steroidal creams inhibit calcineurin, a protein that activates immune cells called T-cells, which contribute to eczema symptoms.
Examples:
Tacrolimus (Protopic)
Pimecrolimus (Elidel)
Potential Side Effects:
Burning or stinging sensation at the application site
Redness or irritation
Increased risk of infections due to suppressed immune response
Biologics: Targeting Eczema's Root Cause
Biologics are a group of new eczema treatments that target specific parts of the immune system, such as overactive cytokines, to alleviate symptoms. They come in two main categories: monoclonal antibodies (Mabs) and Disease-modifying anti-rheumatic drugs (DMARDS).
Examples:
Dupilumab (Dupixent) - a monoclonal antibody that blocks the action of IL-4 and IL-13 cytokines
Crisaborole (Eucrisa) - a PDE4 inhibitor, which is a type of DMARD, that reduces inflammation
Potential Side Effects:
Injection site reactions
Eye irritation or conjunctivitis
Increased risk of infections due to altered immune response
Phototherapy: Healing with Light
Phototherapy uses specific wavelengths of UV light to treat moderate-severe eczema. The treatment works by suppressing overactive immune cells in the skin, reducing inflammation and improving symptoms. UVA and UVB light are the most commonly used forms of phototherapy for eczema.
Examples:
Narrowband UVB therapy
UVA1 therapy
Potential Side Effects:
Skin redness or irritation
Dryness or increased itchiness
Long-term risk of skin cancer with prolonged exposure
Summary
New eczema treatments, including topical calcineurin inhibitors, biologics, and phototherapy, offer innovative approaches to managing eczema. Understanding the mechanisms, examples, and potential side effects of these treatments can help you make informed decisions about your skincare. Remember to consult your healthcare professional before trying any new treatments and to monitor your progress closely.
Biologics: Targeting Eczema's Root Cause
Biologics are a group of new eczema treatments that target specific parts of the immune system, such as overactive cytokines, to alleviate symptoms. They come in two main categories: monoclonal antibodies (Mabs) and Disease-modifying anti-rheumatic drugs (DMARDS).
Examples:
Dupilumab (Dupixent) - a monoclonal antibody that blocks the action of IL-4 and IL-13 cytokines
Crisaborole (Eucrisa) - a PDE4 inhibitor, which is a type of DMARD, that reduces inflammation
Potential Side Effects:
Injection site reactions
Eye irritation or conjunctivitis
Increased risk of infections due to altered immune response
Phototherapy: Healing with Light
Phototherapy uses specific wavelengths of UV light to treat moderate-severe eczema. The treatment works by suppressing overactive immune cells in the skin, reducing inflammation and improving symptoms. UVA and UVB light are the most commonly used forms of phototherapy for eczema.
Examples:
Narrowband UVB therapy
UVA1 therapy
Potential Side Effects:
Skin redness or irritation
Dryness or increased itchiness
Long-term risk of skin cancer with prolonged exposure
Summary
New eczema treatments, including topical calcineurin inhibitors, biologics, and phototherapy, offer innovative approaches to managing eczema. Understanding the mechanisms, examples, and potential side effects of these treatments can help you make informed decisions about your skincare. Remember to consult your healthcare professional before trying any new treatments and to monitor your progress closely.
Biologics: Targeting Eczema's Root Cause
Biologics are a group of new eczema treatments that target specific parts of the immune system, such as overactive cytokines, to alleviate symptoms. They come in two main categories: monoclonal antibodies (Mabs) and Disease-modifying anti-rheumatic drugs (DMARDS).
Examples:
Dupilumab (Dupixent) - a monoclonal antibody that blocks the action of IL-4 and IL-13 cytokines
Crisaborole (Eucrisa) - a PDE4 inhibitor, which is a type of DMARD, that reduces inflammation
Potential Side Effects:
Injection site reactions
Eye irritation or conjunctivitis
Increased risk of infections due to altered immune response
Phototherapy: Healing with Light
Phototherapy uses specific wavelengths of UV light to treat moderate-severe eczema. The treatment works by suppressing overactive immune cells in the skin, reducing inflammation and improving symptoms. UVA and UVB light are the most commonly used forms of phototherapy for eczema.
Examples:
Narrowband UVB therapy
UVA1 therapy
Potential Side Effects:
Skin redness or irritation
Dryness or increased itchiness
Long-term risk of skin cancer with prolonged exposure
Summary
New eczema treatments, including topical calcineurin inhibitors, biologics, and phototherapy, offer innovative approaches to managing eczema. Understanding the mechanisms, examples, and potential side effects of these treatments can help you make informed decisions about your skincare. Remember to consult your healthcare professional before trying any new treatments and to monitor your progress closely.
Dr Noreen Akram
Dr Noreen Akram
Dr Noreen Akram



our journal
our journal
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More insights for you.
More insights for you.
More insights for you.
Explore more reflections, guidance, and practical tools to support your growth and well-being.
Explore more reflections, guidance, and practical tools to support your growth and well-being.
Explore more reflections, guidance, and practical tools to support your growth and well-being.
Your questions.
Answered.
Not sure what to expect? These answers might help you feel more confident as you begin.
Didn’t find your answer? Send us a message at
hello@proton-health.com — we’ll respond with care and clarity.
How is this different to traditional dermatology or telehealth apps?
Most telehealth apps are just video calls with doctors who don't know your history, offering templated advice. Traditional dermatology gives you 7 minutes every few months. Symphony is different — it's an AI that learns your complete skin story and provides personalized guidance 24/7, backed by specialists who review your case. Think of it as a personal trainer for your skin, not just another appointment booking app.
How is this different to traditional dermatology or telehealth apps?
Most telehealth apps are just video calls with doctors who don't know your history, offering templated advice. Traditional dermatology gives you 7 minutes every few months. Symphony is different — it's an AI that learns your complete skin story and provides personalized guidance 24/7, backed by specialists who review your case. Think of it as a personal trainer for your skin, not just another appointment booking app.
Which conditions does Symphony support?
Which conditions does Symphony support?
Symphony is built for chronic skin conditions: acne, eczema, psoriasis, and topical steroid withdrawal (TSW). These are the conditions where understanding your triggers matters most — and where the traditional "here's a cream, see you in 3 months" approach fails hardest. If you're dealing with something else, reach out — we're expanding based on what our members need.
Is my data protected?
Is my data protected?
Your data is encrypted, never sold, and never used for advertising. You can export it. You can delete it anytime. Read our full privacy policy below.
Why not just see a dermatologist more frequently?
Why not just see a dermatologist more frequently?
You could — if you could get an appointment, afford the visit, and somehow give them access to absolutely everything that happened between visits. The reality: your dermatologist sees a snapshot. Symphony sees the full picture — what you ate, how you slept, what products you used, how stressed you were — and connects it to how your skin responded. We're not replacing your dermatologist. We're giving them (and you) context they'd never otherwise have.
How do I know if I'm a good candidate?
How do I know if I'm a good candidate?
If you've been dealing with a chronic skin condition and still don't fully understand why your skin flares — you're a good candidate. Symphony works best for people willing to track consistently (a few minutes a day) and who want to understand their patterns, not just treat symptoms. If you're looking for a quick fix or a magic cream recommendation, we're probably not the right fit.
What if I've tried everything already?
What if I've tried everything already?
Then you're exactly who we built this for. "Tried everything" usually means you've tried a lot of products and treatments — but you've never had the tools to see how your skin actually responds to your life. Symphony doesn't give you more things to try. It helps you understand what's already happening — so the next thing you try is actually informed by your data. It knowing instead of guessing.
Is Symphony a replacement for medical advice?
Is Symphony a replacement for medical advice?
Symphony's AI and tracking tools are not a replacement for medical advice — they help you understand patterns in your own data, but they don't diagnose or prescribe.
That said, we know insights alone aren't always enough. That's why our Premium tier includes referrals to specialist dermatology consultations, gut and skin microbiome testing, and comprehensive lab panels — actual specialists who review your Symphony data.
The app gives you context and understanding. When you need clinical expertise, we connect you with professionals who understand your story.
How is Symphony different from apps that scan your face and sell you products?
How is Symphony different from apps that scan your face and sell you products?
Most "AI skincare" apps take a photo, run it through a basic algorithm, and recommend products they get commission on. They're not trying to help you understand your skin — they're trying to sell you things. Symphony doesn't work that way. We analyze your symptoms, lifestyle, stress, diet, and products over time to find patterns unique to you. We don't sell skincare products directly, and our recommendations are based on your data — not affiliate deals.
When we do recommend products, we're checking thousands of products against YOUR specific sensitivities and triggers. The goal is to stop you wasting money, not to add to the pile of half-used bottles under your sink.
Can I cancel anytime?
Can I cancel anytime?
Yes. No contracts, no cancellation fees. If Symphony isn't working for you, you can cancel in a few clicks. We'd rather earn your trust every month than trap you in one.
Your questions.
Answered.
Not sure what to expect? These answers might help you feel more confident as you begin.
How is this different to traditional dermatology or telehealth apps?
Most telehealth apps are just video calls with doctors who don't know your history, offering templated advice. Traditional dermatology gives you 7 minutes every few months. Symphony is different — it's an AI that learns your complete skin story and provides personalized guidance 24/7, backed by specialists who review your case. Think of it as a personal trainer for your skin, not just another appointment booking app.
How is this different to traditional dermatology or telehealth apps?
Most telehealth apps are just video calls with doctors who don't know your history, offering templated advice. Traditional dermatology gives you 7 minutes every few months. Symphony is different — it's an AI that learns your complete skin story and provides personalized guidance 24/7, backed by specialists who review your case. Think of it as a personal trainer for your skin, not just another appointment booking app.
Which conditions does Symphony support?
Which conditions does Symphony support?
Symphony is built for chronic skin conditions: acne, eczema, psoriasis, and topical steroid withdrawal (TSW). These are the conditions where understanding your triggers matters most — and where the traditional "here's a cream, see you in 3 months" approach fails hardest. If you're dealing with something else, reach out — we're expanding based on what our members need.
Is my data protected?
Is my data protected?
Your data is encrypted, never sold, and never used for advertising. You can export it. You can delete it anytime. Read our full privacy policy below.
Why not just see a dermatologist more frequently?
Why not just see a dermatologist more frequently?
You could — if you could get an appointment, afford the visit, and somehow give them access to absolutely everything that happened between visits. The reality: your dermatologist sees a snapshot. Symphony sees the full picture — what you ate, how you slept, what products you used, how stressed you were — and connects it to how your skin responded. We're not replacing your dermatologist. We're giving them (and you) context they'd never otherwise have.
How do I know if I'm a good candidate?
How do I know if I'm a good candidate?
If you've been dealing with a chronic skin condition and still don't fully understand why your skin flares — you're a good candidate. Symphony works best for people willing to track consistently (a few minutes a day) and who want to understand their patterns, not just treat symptoms. If you're looking for a quick fix or a magic cream recommendation, we're probably not the right fit.
What if I've tried everything already?
What if I've tried everything already?
Then you're exactly who we built this for. "Tried everything" usually means you've tried a lot of products and treatments — but you've never had the tools to see how your skin actually responds to your life. Symphony doesn't give you more things to try. It helps you understand what's already happening — so the next thing you try is actually informed by your data. It knowing instead of guessing.
Is Symphony a replacement for medical advice?
Is Symphony a replacement for medical advice?
Symphony's AI and tracking tools are not a replacement for medical advice — they help you understand patterns in your own data, but they don't diagnose or prescribe.
That said, we know insights alone aren't always enough. That's why our Premium tier includes referrals to specialist dermatology consultations, gut and skin microbiome testing, and comprehensive lab panels — actual specialists who review your Symphony data.
The app gives you context and understanding. When you need clinical expertise, we connect you with professionals who understand your story.
How is Symphony different from apps that scan your face and sell you products?
How is Symphony different from apps that scan your face and sell you products?
Most "AI skincare" apps take a photo, run it through a basic algorithm, and recommend products they get commission on. They're not trying to help you understand your skin — they're trying to sell you things. Symphony doesn't work that way. We analyze your symptoms, lifestyle, stress, diet, and products over time to find patterns unique to you. We don't sell skincare products directly, and our recommendations are based on your data — not affiliate deals.
When we do recommend products, we're checking thousands of products against YOUR specific sensitivities and triggers. The goal is to stop you wasting money, not to add to the pile of half-used bottles under your sink.
Can I cancel anytime?
Can I cancel anytime?
Yes. No contracts, no cancellation fees. If Symphony isn't working for you, you can cancel in a few clicks. We'd rather earn your trust every month than trap you in one.
Didn’t find your answer? Send us a message at
hello@proton-health.com — we’ll respond with care and clarity.
Your questions.
Answered.
Not sure what to expect? These answers might help you feel more confident as you begin.
Didn’t find your answer? Send us a message at
hello@proton-health.com — we’ll respond with care and clarity.
How is this different to traditional dermatology or telehealth apps?
Most telehealth apps are just video calls with doctors who don't know your history, offering templated advice. Traditional dermatology gives you 7 minutes every few months. Symphony is different — it's an AI that learns your complete skin story and provides personalized guidance 24/7, backed by specialists who review your case. Think of it as a personal trainer for your skin, not just another appointment booking app.
How is this different to traditional dermatology or telehealth apps?
Most telehealth apps are just video calls with doctors who don't know your history, offering templated advice. Traditional dermatology gives you 7 minutes every few months. Symphony is different — it's an AI that learns your complete skin story and provides personalized guidance 24/7, backed by specialists who review your case. Think of it as a personal trainer for your skin, not just another appointment booking app.
Which conditions does Symphony support?
Which conditions does Symphony support?
Symphony is built for chronic skin conditions: acne, eczema, psoriasis, and topical steroid withdrawal (TSW). These are the conditions where understanding your triggers matters most — and where the traditional "here's a cream, see you in 3 months" approach fails hardest. If you're dealing with something else, reach out — we're expanding based on what our members need.
Is my data protected?
Is my data protected?
Your data is encrypted, never sold, and never used for advertising. You can export it. You can delete it anytime. Read our full privacy policy below.
Why not just see a dermatologist more frequently?
Why not just see a dermatologist more frequently?
You could — if you could get an appointment, afford the visit, and somehow give them access to absolutely everything that happened between visits. The reality: your dermatologist sees a snapshot. Symphony sees the full picture — what you ate, how you slept, what products you used, how stressed you were — and connects it to how your skin responded. We're not replacing your dermatologist. We're giving them (and you) context they'd never otherwise have.
How do I know if I'm a good candidate?
How do I know if I'm a good candidate?
If you've been dealing with a chronic skin condition and still don't fully understand why your skin flares — you're a good candidate. Symphony works best for people willing to track consistently (a few minutes a day) and who want to understand their patterns, not just treat symptoms. If you're looking for a quick fix or a magic cream recommendation, we're probably not the right fit.
What if I've tried everything already?
What if I've tried everything already?
Then you're exactly who we built this for. "Tried everything" usually means you've tried a lot of products and treatments — but you've never had the tools to see how your skin actually responds to your life. Symphony doesn't give you more things to try. It helps you understand what's already happening — so the next thing you try is actually informed by your data. It knowing instead of guessing.
Is Symphony a replacement for medical advice?
Is Symphony a replacement for medical advice?
Symphony's AI and tracking tools are not a replacement for medical advice — they help you understand patterns in your own data, but they don't diagnose or prescribe.
That said, we know insights alone aren't always enough. That's why our Premium tier includes referrals to specialist dermatology consultations, gut and skin microbiome testing, and comprehensive lab panels — actual specialists who review your Symphony data.
The app gives you context and understanding. When you need clinical expertise, we connect you with professionals who understand your story.
How is Symphony different from apps that scan your face and sell you products?
How is Symphony different from apps that scan your face and sell you products?
Most "AI skincare" apps take a photo, run it through a basic algorithm, and recommend products they get commission on. They're not trying to help you understand your skin — they're trying to sell you things. Symphony doesn't work that way. We analyze your symptoms, lifestyle, stress, diet, and products over time to find patterns unique to you. We don't sell skincare products directly, and our recommendations are based on your data — not affiliate deals.
When we do recommend products, we're checking thousands of products against YOUR specific sensitivities and triggers. The goal is to stop you wasting money, not to add to the pile of half-used bottles under your sink.
Can I cancel anytime?
Can I cancel anytime?
Yes. No contracts, no cancellation fees. If Symphony isn't working for you, you can cancel in a few clicks. We'd rather earn your trust every month than trap you in one.

